Brain, ganglioglioma

Details
Disease Category
Gender
Age
39 years
Organ System/Discipline
Diagnosis
Ganglioglioma
Clinical History

39-year-old woman with refractory epilepsy. Neuroimaging shows an anterior mesial temporal lesion within the amygdala.

Case Discussion

Gangliogliomas are benign tumours usually occurring in children and young adults. They are classified as WHO grade I. Microscopically, they are composed of dysplastic ganglion cells along with a neoplastic glial (astrocytic-like) component. The background often contains numerous eosinophilic granular bodies, which appear as round globular aggregates that ultrastructurally are located within astrocytic processes. BRAF V600E mutation is common. Prognosis is generally excellent with surgical resection.

Image Contributors
Gao, A., Kiehl, TR.

Cite

Gao, A., Kiehl, TR. Brain, ganglioglioma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published . Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/brain-ganglioglioma-lmp65867