Breast, Paget disease

Details
Disease Category
Gender
Age
43 years
Organ System/Discipline
Diagnosis
Paget disease
Clinical History

Diffuse breast asymmetry with skin changes

Case Discussion

Paget disease is a rare form of breast cancer, presenting as skin changes. Tumor cells involve the junction between the nipple stroma and epidermis, without invasion across the basement membrane. This disruption causes the exudative skin changes. It is classified as a form of ductal carcinoma in situ, owing to the lack of invasion. However, Paget disease can be associated with an underlying invasive carcinoma.

Image Contributors
Chang, M.

Cite

Chang, M. Breast, Paget disease. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published . Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/breast-paget-disease-lmp35661