Duodenum, tubular adenoma

Details
Disease Category
Gender
Age
43 years
Organ System/Discipline
Diagnosis
Tubular adenoma with low grade dysplasia
Clinical History

Patient underwent a subtotal colectomy with ileo-rectal anastomosis. He is known to have 25-50 small polyps in the remaining rectum. During routine upper endoscopy, the following polyps were seen in the duodenum.

Case Discussion

After the colorectum, the duodenum is the second most commonly affected site to polyp development in Familial Adenomatous Polyposis (FAP). Duodenal/periampullary adenocarcinoma is the leading cause of death in FAP after colorectal cancer. While greater than 95% of FAP patients develop adenomatous polyps in the duodenum during their lifetime, only 5% go on to develop cancer. Routine screening with upper gatrointestinal endoscopy is now commonplace in an attempt to decrease the cancer rate. This image, and its supplementary image, show 2 duodenal adenomas from the same patient.

Image Contributors
Forse, C., Chang, M.

Lists containing this slide

Cite

Forse, C., Chang, M. Duodenum, tubular adenoma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published . Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/duodenum-tubular-adenoma-lmp56898