Large intestine, Dedifferentiated gastrointestinal stromal tumour (GIST), IC117

Details
Disease Category
Gender
Age
62 years
Organ System/Discipline
Diagnosis
Dedifferentiated gastrointestinal stromal tumour (GIST)
Clinical History

Large bowel lesion.

Case Discussion

Key histologic features: As with other GISTs, but pleomorphism; brisk mitoses.

Molecular: +PDGFRA.

NB: Chronic imatinib (see related content for reference).

Image Contributors
Armstrong, S., Dickson, B.
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Cite

Armstrong, S., Dickson, B. Large intestine, Dedifferentiated gastrointestinal stromal tumour (GIST), IC117. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published . Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/large-intestine-dedifferentiated-gastrointestinal-stromal-tumour-gist-ic117-lmp96328