Incidental finding at sentinel lymph node biopsy for breast cancer. Otherwise asymptomatic.
Case Discussion
Follicular lymphoma is a non-Hodgkin B-cell lymphoma that is often indolent. The cells resemble lymphoid germinal centre B-cells, and often demonstrate a t(14,18) translocation with overexpression of the anti-apoptotic protein bcl2. WHO grading of follicular lymphoma depends on the number of large centroblasts within the tumour. In this case, centroblasts exceed 15 per high-power fields, without solid sheet-like growth. This meets the criteria for Grade 3A.
Image Contributors
Chang, M.
Cite
Chang, M. Lymph node, follicular lymphoma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/lymph-node-follicular-lymphoma-lmp58237
