B-Lymphoblastic leukemia lymphoma can have myeloid antigens which if it fulfills the World Health Organization's 2017 criteria, is considered a mixed-phenotype acute leukemia. Those very rarely present as a tissue mass. Myeloid sarcoma (tissue mass) more commonly a presentation of myelomonocytic or myeloid leukemias (AML).
Morgan, S. Neck, Mixed-phenotype acute leukemia, H&E Stain. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/neck-mixed-phenotype-acute-leukemia-he-stain-lmp57383
