Skin, Involuting infantile hemangioma, GLUT1 stain

Infantile hemangioma is a common vascular tumour of infancy. The most common sites of involvement are skin and soft-tissue of the face, head, and neck. In this excisional biopsy, the dermis and subcutaneous tissue contains sparse proliferation of capillary sized vessels .The walls are generally thin, with some vessels having thicker and sclerotic walls due to involution. However in some areas, the endothelial cells are plump and protrude into the lumen. The dermis contains scattered chronic inflammation and scar tissue.

Infantile hemangiomas are strongly immunoreactive for GLUT1.

This slide shows GLUT1 stain. See Related Content for H&E stain.