62 year-old mail with yellow-tan plaque on his right lower leg.
Case Discussion
Irritated seborrheic keratosis is a benign keratinocytic proliferation, generally occurring in older adults. Sections show acanthosis, hyperkeratosis with pronounced reactive appearance including squamous whorls and scattered mitotic figures. There is generally surface crusting. The appearance may be mistaken for well differentiated squamous cell carcinoma.
Image Contributors
Boles, D., Sade, S.
Cite
Boles, D., Sade, S. Skin, Irritated seborrheic keratosis. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/skin-irritated-seborrheic-keratosis-lmp61653
