Stomach, granulomatous gastritis

Granulomatous gastritis is a descriptive diagnosis used when granulomas are observed in gastric mucosa. The most common causes of granulomatous inflammation in the stomach include sarcoidosis, Crohn's disease, foreign material, infections (i.e. TB, histoplasma capsulatum, syphilis), common variable immunodeficiency and systemic vasculitides (i.e. Wegener's granulomatosis). In addition to granulomas, Crohn's disease in the stomach may also manifest as (1) focally enhanced gastritis characterized by lymphocytes and neutrophils around single crypts with minimal inflammation in the adjacent gastric mucosa and/or (2) antral stenosis.