Details
Disease Category
Gender
Age
32 years
Organ System/Discipline
Diagnosis
Mixed germ cell tumour
Clinical History
Self-detected 4.5 cm testicular mass.
Case Discussion
The overwhelming majority of testicular tumours are derived from germ cells. There are different histologic subtypes of germ cell tumours which are generally divided in seminomatous and non-seminomatous tumours. Germ cell tumours may be composed of a single histologic subtype, but it is more common for it to be composed of two or more subtypes (as in this case).
The tumour was composed of 97% embryonal carcinoma, 2% yolk sac tumour, and 1% teratoma. There was lymphovascular invasion as well as involvement of the rete testis. There is notable hemorrhage and necrosis. The seminiferous tubules do not appear entirely normal, with features suggestive of intratubular germ cell neoplasia.
Image Contributors
Hodgson, A., Sugar, L.
Cite
Hodgson, A., Sugar, L. Testis, Mixed germ cell tumour. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/testis-mixed-germ-cell-tumour-lmp54949