52 year old woman presented with abnormal uterine bleeding; hysterectomy for uterine mass.
Case Discussion
Leiomyoma with bizarre nuclei (previously known as symplastic/atypical leiomyoma), is a benign uterine smooth muscle neoplasm which can be mistaken histologically for leiomyosarcoma. The tumour shows atypical pleomorphic smooth muscle cells with occasional binucleated/multinucleated cells; however, neither increased mitotic figures nor coagulative tumor cell necrosis is identified.
Image Contributors
Hindi, K., Chang, M.
Cite
Hindi, K., Chang, M. Uterus, Atypical leiomyoma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/uterus-atypical-leiomyoma-lmp14220