Uterus, leiomyosarcoma

Details
Disease Category
Gender
Age
46 years
Organ System/Discipline
Diagnosis
Uterine leiomyosarcoma with extensive lymphovascular invasion
Clinical History

11 cm pelvic mass.

Case Discussion

Uterine leiomyosarcoma is a rare malignant smooth muscle tumour, representing fewer than 1% of all uterine malignancies. It is the most frequently occuring uterine mesenchymal malignancy. Uterine leiomyosarcomas exhibit aggressive growth, local recurrence, and frequent distant metastasis (commonly to lung and liver). They present as solitary large dominant masses (often greater than 10cm) with fish-flesh like consistency and indistinct bundling. Diagnosis relies on the evaluation of the coagulative tumour necrosis, mitotic activity and significant, diffuse atypia.

Image Contributors
Azordegan, N., Ismiil, N.

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Cite

Azordegan, N., Ismiil, N. Uterus, leiomyosarcoma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published . Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/uterus-leiomyosarcoma-lmp91313