Dedifferentiated liposarcoma is a malignant soft tissue tumour that can be difficult to diagnose owing the relative lack of a clear adipocytic component. It most commonly involves the retroperitoneum. The features are of an intermediate to high-grade spindle cell sarcoma. In this case, meningothelial whorls and metaplastic bone can also be seen.
Image Contributors
Dickson, B., Nanji, S., Chang, M.
Cite
Dickson, B., Nanji, S., Chang, M. Soft Tissue, Dedifferentiated liposarcoma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/soft-tissue-dedifferentiated-liposarcoma-lmp84097