Skin, Dermatofibroma

Details
Disease Category
Gender
Age
38 years
Organ System/Discipline
Diagnosis
Dermatofibroma
Clinical History

Reddish-brown papule occurring on the lower extremity.

Case Discussion

Dermatofibroma is a common, benign neoplasm which is a moderately well-circumscribed dermal-based proliferation of spindled to histiocytoid appearing cells. There is often overlying epidermal hyperplasia (seen in this case), but also melanocytic and folliculosebaceous hyperplasia. At the tumour periphery, there is "collagen trapping" by lesional cells. There are numerous variants of dermatofibroma, the most common including aneurysmal fibrous histiocytoma, epithelioid cell histiocytoma and cellular fibrous histiocytoma.

Image Contributors
Forse, C., Ghazarian, D.

Cite

Forse, C., Ghazarian, D. Skin, Dermatofibroma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published . Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/skin-dermatofibroma-lmp10387