Details
Disease Category
Gender
Age
49 years
Organ System/Discipline
Diagnosis
Adenoid cystic carcinoma
Clinical History
49 year old female with breast mass.
Case Discussion
Mammary adenoid cystic carcinoma is very rare. Although triple negative, it is one of the more indolent breast cancers if completely excised. This tumour is morphologically identical to its counterpart in the salivary gland.
Adenoid cystic carcinoma is characterized by a dual-cell population: a ductal-luminal, and myoepithelial-basaloid. The overall architecture can be cribriform, trabecular, or solid. It harbours recurrent chromosomal translocation t(6:9) involving MYB and NFIB genes.
The differential diagnosis includes collagenous spherulosis, cribriform DCIS, and cribriform carcinoma.
Image Contributors
Boles, D., Mete, O.
Cite
Boles, D., Mete, O. Breast, Adenoid cystic carcinoma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/breast-adenoid-cystic-carcinoma-lmp23525