Breast, Metastatic breast cancer, GATA3 Stain

Breast, Metastatic breast cancer, H&E Stain
Details
Disease Category
Gender
Organ System/Discipline
Clinical History

Ascites and peritoneal carcinomatosis. Elevated CA-125. Indeterminate ovarian lesion on imaging.

Case Discussion

This patient presented with a clinical history suspicious for an ovarian malignancy, and within the patient's chart, it was stated that she had a 'recent diagnosis of advanced ovarian cancer'. Of note, the patient has a history of a T1bN0 grade 2 invasive ductal carcinoma and lobular carcinoma in situ two years prior to her current presentation.

Cytology (at an outside hospital) of her paracentesis fluid showed the following immunohistochemistry profile:

Positive for CK7, PAX8 (moderate), and WT1 (moderate).
Negative for S100, CD45, CD20, CD3, CDX2, TTF1.

Diagnosis
Metastatic breast cancer
Breast, Metastatic breast cancer, PAX8 Stain
Details
Disease Category
Gender
Organ System/Discipline
Clinical History

Ascites and peritoneal carcinomatosis. Elevated CA-125. Indeterminate ovarian lesion on imaging.

Case Discussion

This patient presented with a clinical history suspicious for an ovarian malignancy, and within the patient's chart, it was stated that she had a 'recent diagnosis of advanced ovarian cancer'. Of note, the patient has a history of a T1bN0 grade 2 invasive ductal carcinoma and lobular carcinoma in situ two years prior to her current presentation.

Cytology (at an outside hospital) of her paracentesis fluid showed the following immunohistochemistry profile:

Positive for CK7, PAX8 (moderate), and WT1 (moderate).
Negative for S100, CD45, CD20, CD3, CDX2, TTF1.

Diagnosis
Metastatic breast cancer
Breast, Metastatic breast cancer, WT1 Stain
Details
Disease Category
Gender
Organ System/Discipline
Clinical History

Ascites and peritoneal carcinomatosis. Elevated CA-125. Indeterminate ovarian lesion on imaging.

Case Discussion

This patient presented with a clinical history suspicious for an ovarian malignancy, and within the patient's chart, it was stated that she had a 'recent diagnosis of advanced ovarian cancer'. Of note, the patient has a history of a T1bN0 grade 2 invasive ductal carcinoma and lobular carcinoma in situ two years prior to her current presentation.

Cytology (at an outside hospital) of her paracentesis fluid showed the following immunohistochemistry profile:

Positive for CK7, PAX8 (moderate), and WT1 (moderate).
Negative for S100, CD45, CD20, CD3, CDX2, TTF1.

Diagnosis
Metastatic breast cancer
Breast, Metastatic breast cancer, GATA3 Stain
Details
Disease Category
Gender
Organ System/Discipline
Clinical History

Ascites and peritoneal carcinomatosis. Elevated CA-125. Indeterminate ovarian lesion on imaging.

Case Discussion

This patient presented with a clinical history suspicious for an ovarian malignancy, and within the patient's chart, it was stated that she had a 'recent diagnosis of advanced ovarian cancer'. Of note, the patient has a history of a T1bN0 grade 2 invasive ductal carcinoma and lobular carcinoma in situ two years prior to her current presentation.

Cytology (at an outside hospital) of her paracentesis fluid showed the following immunohistochemistry profile:

Positive for CK7, PAX8 (moderate), and WT1 (moderate).
Negative for S100, CD45, CD20, CD3, CDX2, TTF1.

Diagnosis
Metastatic breast cancer