Details
Right breast fungating mass, circumscribed, 20 cm.
Malignant phyllodes tumours are fibroepithelial neoplasms with malignant stromal growth. Criteria for malignancy included stromal overgrowth, stromal hypercellularity, stromal cell atypia, mitotic activity, and invasive tumour borders. In this case, areas of osteoid and cartilage with malignant cells can be seen.
Shown here is the presence of both stromal overgrowth and a fibroepithelial component. Both chondroid and osteoid elements are also present in this slide.
Details
Right breast fungating mass, circumscribed, 20 cm.
Malignant phyllodes tumours are fibroepithelial neoplasms with malignant stromal growth. Criteria for malignancy included stromal overgrowth, stromal hypercellularity, stromal cell atypia, mitotic activity, and invasive tumour borders. In this case, areas of osteoid and cartilage with malignant cells can be seen.
Shown here is an area of marked cellularity and extensive stromal overgrowth. Necrosis is also present.
Details
Right breast fungating mass, circumscribed, 20 cm.
Malignant phyllodes tumours are fibroepithelial neoplasms with malignant stromal growth. Criteria for malignancy included stromal overgrowth, stromal hypercellularity, stromal cell atypia, mitotic activity, and invasive tumour borders. In this case, areas of osteoid and cartilage with malignant cells can be seen.
Shown here is a circumscribed border with surrounding breast tissue.