Details
Disease Category
Gender
Age
39 years
Organ System/Discipline
Diagnosis
Clear cell meningioma
Clinical History
39-year-old man with several-months history of headache, dizziness, hearing loss in the right ear with persistent tinnitus, facial numbness on the right, and diplopia. Neuroimaging shows right cerebello-pontine angle mass.
Case Discussion
Clear cell meningiomas are a rare variant of meningioma classified as WHO grade II. They typically present in younger patients, usually in the cerebello-pontine angle or cauda equina region. They are composed of polygonal cells with cytoplasmic clearing due to glycogen accumulation, which stains with PAS. Classic features of meningioma, such as whorls and psammoma bodies, are rare. Clear cell meningiomas behave more aggressively, with frequent recurrence and occasional CSF seeding.
Image Contributors
Gao, A., Munoz, D.
Cite
Gao, A., Munoz, D. Brain, Clear cell meningioma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/brain-clear-cell-meningioma-lmp67858