Kidney, Mucinous tubular and spindle cell carcinoma

Details
Disease Category
Gender
Age
54 years
Organ System/Discipline
Diagnosis
Mucinous tubular and spindle cell carcinoma
Clinical History

Left partial nephrectomy for a tumour measuring 4.8 cm in a 54 year old male.

Case Discussion

Mucinous tubular and spindle cell carcinoma is a relatively rare neoplasm, accounting for less than 1% of all renal neoplasms. It is characterized by a low-grade biphasic carcinoma, and it is usually associated with a favorable prognosis. Grossly, it is often a well-circumscribed mass with gray-white to tan or yellow cut surface, usually centered in the medulla of the kidney.

The section shows a well-circumscribed mass with tightly packed elongated, branching tubules lined by low columnar or cuboidal, with uniform, low-grade, round nuclei. There are scattered areas of foamy macrophages among the tubules. The bland spindle cells appear to be intimately admixed with the tubular component. The juxtaposition of these 2 features is typical in mucinous tubular and spindle cell carcinoma.

Image Contributors
Shao, T., Mete, O.

Cite

Shao, T., Mete, O. Kidney, Mucinous tubular and spindle cell carcinoma. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published . Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/kidney-mucinous-tubular-and-spindle-cell-carcinoma-lmp73365