Ascites and peritoneal carcinomatosis. Elevated CA-125. Indeterminate ovarian lesion on imaging.
Case Discussion
This patient presented with a clinical history suspicious for an ovarian malignancy, and within the patient's chart, it was stated that she had a 'recent diagnosis of advanced ovarian cancer'. Of note, the patient has a history of a T1bN0 grade 2 invasive ductal carcinoma and lobular carcinoma in situ two years prior to her current presentation.
Cytology (at an outside hospital) of her paracentesis fluid showed the following immunohistochemistry profile:
Positive for CK7, PAX8 (moderate), and WT1 (moderate).
Negative for S100, CD45, CD20, CD3, CDX2, TTF1.
Pun, C., Conner, J. Breast, Metastatic breast cancer, H&E Stain. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/breast-metastatic-breast-cancer-he-stain-lmp23048