Ascites and peritoneal carcinomatosis. Elevated CA-125. Indeterminate ovarian lesion on imaging.
Case Discussion
This patient presented with a clinical history suspicious for an ovarian malignancy, and within the patient's chart, it was stated that she had a 'recent diagnosis of advanced ovarian cancer'. Of note, the patient has a history of a T1bN0 grade 2 invasive ductal carcinoma and lobular carcinoma in situ two years prior to her current presentation.
Cytology (at an outside hospital) of her paracentesis fluid showed the following immunohistochemistry profile:
Positive for CK7, PAX8 (moderate), and WT1 (moderate).
Negative for S100, CD45, CD20, CD3, CDX2, TTF1.
Pun, C., Conner, J. Breast, Metastatic breast cancer, WT1 Stain. Digital Laboratory Medicine Library, Dept of Laboratory Medicine & Pathobiology, University of Toronto. Published
. Accessed December 17, 2025. https://dev.dlml.cflabs.ca/image/breast-metastatic-breast-cancer-wt1-stain-lmp73499
